Saliva Test for Microbial Evaluation of Caries Risk

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Dental caries has been an important public health problem worldwide. Information about an individual’s caries risk and state of carious lesions should be used in making a personalised treatment plan. Recent studies have successfully identified patients with a high or low risk of primary caries by using Classification and Regression Trees (CART) according to the number of specific cariogenic bacteria, as well as those at risk of secondary caries according to the number of particular bacteria and previous caries experience. The same study also provides information regarding how long it takes to develop a new carious lesion for each high and low risk group. This information assists in planning a personalised regular preventive program with an interval appropriate to the individual’s risk of caries.


Biological Analysis accessible to practitioners
Cario-Analyse: Salivary diagnosis of the risk of caries
Quantitative and qualitative diagnosis of bacterial load with the identification of:

  • Lactobacillus spp
  • Streptococcus mutans

Lactobacillus spp.
The genus Lactobacillus currently contains over 180 species and encompasses a wide variety of organisms. Major species are L. casei group, and the species L. acidophilus, L. salivarius, and L. reuteri. They are a major part of the lactic acid bacteria group (i.e. they convert sugars to lactic acid). For human beings, they constitute a significant component of the microbiota of saliva and are responsible of acid production and low pH environment.

Streptococcus mutans
A cariogenic microorganism that breaks down sugar for energy and produces an acidic environment, which demineralizes the superficial structure of the tooth. Transmission of S. mutans can be found in people of all ages although it is more common in infants and children. There is transmission of S. mutans from mother to child.

The Method
Detection and quantification of pathogens in real-time PCR from saliva and buffer capacity dosage.

Cario-Analyse Report
Tool for prevention and treatment support
Individualised monitoring to assist in determining therapeutic management.
Motivation and patient involvement